Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis

The bidirectional interaction between carcinogens and gut microbiota that contributes to colorectal cancer is complicated. Reactivation of carcinogen metabolites by microbial β-glucuronidase (βG) in the gut potentially plays an important role in colorectal carcinogenesis. We assessed the chemoprotec...

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Principais autores:	Kai-Wen Cheng, Chih-Hua Tseng, I.-Ju Chen, Bo-Cheng Huang, Hui-Ju Liu, Kai-Wen Ho, Wen-Wei Lin, Chih-Hung Chuang, Ming-Yii Huang, Yu-Lin Leu, Steve R. Roffler, Jaw-Yuan Wang, Yeh-Long Chen, Tian-Lu Cheng
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2022-03-01
סדרה:	Pharmacological Research
נושאים:	Gut microbiota Carcinogens Gut microbial βG Chemoprevention Colorectal cancer
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S1043661822000603
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