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Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system

SUMMARY Toll-like receptors (TLRs) are an important class of pattern recognition receptors (PRRs) that recognize microbial and danger signals. Their downstream signaling upon ligand binding is vital for initiation of the innate immune response. In human and mammalian models, myeloid differentiation...

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Príomhchruthaitheoirí: Michiel van der Vaart, Joost J. van Soest, Herman P. Spaink, Annemarie H. Meijer
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: The Company of Biologists 2013-05-01
Sraith:Disease Models & Mechanisms
Rochtain ar líne:http://dmm.biologists.org/content/6/3/841
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