Shiga toxin increases formation of clathrin-coated pits through Syk kinase.
Clathrin-dependent endocytosis is a main entry mechanism for the glycolipid-binding Shiga toxin (Stx), although clathrin-independent pathways are also involved. Binding of Stx to its receptor Gb3 not only is essential for Stx retrograde transport to the endoplasmic reticulum and toxicity but also ac...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science (PLoS)
2010-07-01
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| Collection: | PLoS ONE |
| Accès en ligne: | http://europepmc.org/articles/PMC2910670?pdf=render |
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