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LncRNA GAS5 restrains ISO-induced cardiac fibrosis by modulating mir-217 regulation of SIRT1

Abstract Considering the effect of SIRT1 on improving myocardial fibrosis and GAS5 inhibiting occurrence and development of myocardial fibrosis at the cellular level, the aim of the present study was to investigate whether LncRNA GAS5 could attenuate cardiac fibrosis through regulating mir-217/SIRT1...

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Principais autores: Yan-hong Zhang, Ting-ting Sun, Zhen-hua Liu, Xu Li, Xiao-Fang Fan, Li-ping Han
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2024-04-01
Series:Scientific Reports
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Acceso en liña:https://doi.org/10.1038/s41598-024-58239-9
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