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RSC primes the quiescent genome for hypertranscription upon cell-cycle re-entry

Quiescence is a reversible G0 state essential for differentiation, regeneration, stem-cell renewal, and immune cell activation. Necessary for long-term survival, quiescent chromatin is compact, hypoacetylated, and transcriptionally inactive. How transcription activates upon cell-cycle re-entry is un...

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Principais autores: Christine E Cucinotta, Rachel H Dell, Keean CA Braceros, Toshio Tsukiyama
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2021-05-01
Serier:eLife
Fag:
quiescence
chromatin
transcription
chromatin remodeling
RSC
quiescence exit
Online adgang:https://elifesciences.org/articles/67033
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