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Longitudinal association of cumulative risk factors in early life, genetic risk, and healthy lifestyles during adulthood with the risk of type 2 diabetes

Abstract Background The combined influence of early life risk factors on the type 2 diabetes (T2D) development is not well-studied, and it is unclear whether these associations can by modified by genetic risk and healthy lifestyles in later life. Methods We studied 148,621 participants in the UK Bio...

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Uloženo v:
Hlavní autoři: Jiajin Hu, Honghao Yang, Yilin Liu, Lu Zheng, Xiaoyan Zhang, Jing Yang, Zhe Yang, Xiaochuan Wang, Borui Liu, Hong Cui, Izzuddin M Aris, Yang Xia
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-04-01
Edice:BMC Medicine
Témata:
Type 2 Diabetes
Early Childhood Risk Factors
Genetic Predisposition
Healthy Lifestyle
Dose Response
On-line přístup:https://doi.org/10.1186/s12916-025-04025-x
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