Lem3, a phospholipid flippase subunit, influences Candida albicans pathogenicity through maintenance of plasma membrane asymmetry

ABSTRACT Flippases, composed of catalytic and regulatory subunits, preserve cellular integrity by maintaining the asymmetric distribution of phospholipids across the plasma membrane. Here, we provide the first functional characterization of Lem3, the regulatory subunit of the flippase complex in Can...

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Autores principales:	Pranjali Agrawal, Pritam Kumar, Basharat Ali, Sunna Nabeela, Mélanie A. C. Ikeh, Joachim Morschhäuser, David R. Andes, Clarissa J. Nobile, Rajendra Prasad, Priya Uppuluri, Sneh Lata Panwar
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology 2026-05-01
Colección:	Microbiology Spectrum
Materias:	P4-type ATPases flippase Lem3 Candida albicans virulence biofilms
Acceso en línea:	https://journals.asm.org/doi/10.1128/spectrum.02965-25
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