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Stepwise release of biologically active HMGB1 during HSV-2 infection.

BACKGROUND: High mobility group box 1 protein (HMGB1) is a major endogenous danger signal that triggers inflammation and immunity during septic and aseptic stresses. HMGB1 recently emerged as a key soluble factor in the pathogenesis of various infectious diseases, but nothing is known of its behavio...

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Autors principals: Chloé Borde, Stéphanie Barnay-Verdier, Claire Gaillard, Hakim Hocini, Vincent Maréchal, Joël Gozlan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3023802?pdf=render
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