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Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration

The new concept of mammalian sex maintenance establishes that particular key genes must remain active in the differentiated gonads to avoid genetic sex reprogramming, as described in adult ovaries after Foxl2 ablation. Dmrt1 plays a similar role in postnatal testes, but the mechanism of adult testis...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Francisco J Barrionuevo, Alicia Hurtado, Gwang-Jin Kim, Francisca M Real, Mohammed Bakkali, Janel L Kopp, Maike Sander, Gerd Scherer, Miguel Burgos, Rafael Jiménez
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: eLife Sciences Publications Ltd 2016-06-01
Цуврал:eLife
Нөхцлүүд:
Онлайн хандалт:https://elifesciences.org/articles/15635
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