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Ibuprofen-Loaded Chitosan–Lipid Nanoconjugate Hydrogel with Gum Arabic: Green Synthesis, Characterisation, In Vitro Kinetics Mechanistic Release Study and PGE2 Production Test

Ibuprofen is a well-known non-steroidal anti-inflammatory (NSAID) medicine that is often used to treat inflammation in general. When given orally, it produces gastrointestinal issues which lead to lower patient compliance. Ibuprofen transdermal administration improves both patient compliance and the...

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Main Authors: Syed Mahmood, Samah Hamed Almurisi, Khater AL-Japairai, Ayah Rebhi Hilles, Walla Alelwani, Azzah M. Bannunah, Farhan Alshammari, Fawaz Alheibshy
Format: Artigo
Language:Inglês
Published: MDPI AG 2021-12-01
Series:Gels
Subjects:
ibuprofen
chitosan
green synthesis
transdermal
nanoconjugate
hydrogel
Online Access:https://www.mdpi.com/2310-2861/7/4/254
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