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Direct C–H amination reactions of arenes with N-hydroxyphthalimides catalyzed by cuprous bromide

An efficient Cu-catalyzed strategy for the direct C–H amination of arenes in high yields using N-hydroxyphthalimide as the amidyl radical precursor under air is reported. A possible mechanism is proposed that proceeds via a radical reaction in the presence of CuBr and triethyl phosphite.

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Principais autores: Dongming Zhang, Bin Lv, Pan Gao, Xiaodong Jia, Yu Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2022-06-01
coleção:Beilstein Journal of Organic Chemistry
Assuntos:
Acesso em linha:https://doi.org/10.3762/bjoc.18.65
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