Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia

Summary: The strategy of lowering cholesterol levels by promoting cholesterol excretion is still lacking, and few molecular targets act on multiple cholesterol metabolic processes. In this study, we find that Nogo-B deficiency/inhibition simultaneously promotes hepatic uptake of cholesterol and chol...

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Auteurs principaux:	Chao Xue, Peng Zeng, Ke Gong, Qian Li, Zian Feng, Mengyao Wang, Shasha Chen, Yanfang Yang, Jiaqi Li, Shuang Zhang, Zequn Yin, Yingquan Liang, Tengteng Yan, Miao Yu, Ke Feng, Dan Zhao, Xiaoxiao Yang, Xia Zhang, Likun Ma, Yasuko Iwakiri, Liang Chen, Xiaoqiang Tang, Yuanli Chen, Houzao Chen, Yajun Duan
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2024-09-01
Collection:	Cell Reports
Sujets:	CP: Metabolism
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2211124724010428
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