Liver macrophage-derived exosomal miRNA-342-3p promotes liver fibrosis by inhibiting HPCAL1 in stellate cells

Abstract Background The progression of liver fibrosis involves complex interactions between hepatic stellate cells (HSCs) and multiple immune cells in the liver, including macrophages. However, the mechanism of exosomes in the crosstalk between liver macrophages and HSCs remains unclear. Method Exos...

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Hlavní autoři:	Wenshuai Li, Lirong Chen, Qi Zhou, Tiansheng Huang, Wanwei Zheng, Feifei Luo, Zhong Guang Luo, Jun Zhang, Jie Liu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-02-01
Edice:	Human Genomics
Témata:	Liver fibrosis Liver macrophage Exosome Hepatic stellate cells MiRNA-342-3p
On-line přístup:	https://doi.org/10.1186/s40246-025-00722-z
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