Inhibition of gasdermin D-dependent pyroptosis attenuates the progression of silica-induced pulmonary inflammation and fibrosis

Silicosis is a leading cause of occupational disease-related morbidity and mortality worldwide, but the molecular basis underlying its development remains unclear. An accumulating body of evidence supports gasdermin D (GSDMD)-mediated pyroptosis as a key component in the development of various pulmo...

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Detalles Bibliográficos

Principais autores:	Meiyue Song, Jiaxin Wang, Youliang Sun, Junling Pang, Xiaona Li, Yuan Liu, Yitian Zhou, Peiran Yang, Tianhui Fan, Ying Liu, Zhaoguo Li, Xianmei Qi, Baicun Li, Xinri Zhang, Jing Wang, Chen Wang
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2022-03-01
Series:	Acta Pharmaceutica Sinica B
Assuntos:	Silicosis Gasdermin D Pyroptosis Macrophage Pulmonary fibrosis
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2211383521003981
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