Sunitinib Treatment for Advanced Paraganglioma: Case Report of a Novel SDHD Gene Mutation Variant and Systematic Review of the Literature

BackgroundParagangliomas (PGLs) are neuroendocrine neoplasms arising from chromaffin cells of sympathetic or parasympathetic paraganglia. Systemic therapies have been used only in metastatic PGLs. Antiangiogenic agents, such as sunitinib, could be a viable therapeutic choice in the subgroup of patie...

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Detalhes bibliográficos

Principais autores:	Franz Sesti, Tiziana Feola, Giulia Puliani, Roberta Centello, Valentina Di Vito, Oreste Bagni, Andrea Lenzi, Andrea M. Isidori, Vito Cantisani, Antongiulio Faggiano, Elisa Giannetta
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-06-01
coleção:	Frontiers in Oncology
Assuntos:	sunitinib paraganglioma Familial Paraganglioma Syndrome succinate dehydrogenase SDHD
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2021.677983/full
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