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Manipulation of regulators of morphogenesis is not sufficient to render a Candida albicans colonizer strain pathogenic

ABSTRACT As a member of the microbiome, Candida albicans colonizes the oral cavity and other mucosal surfaces of the human body. While commensalism is tightly controlled by the host immune system, the fungal determinants enabling the fungus to colonize the host mucosa without causing tissue damage a...

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Principais autores: Ricardo Fróis-Martins, Sarah Mertens, Van Du T. Tran, Corinne Maufrais, Christophe d'Enfert, Dominique Sanglard, Salomé LeibundGut-Landmann
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2026-05-01
coleção:mBio
Assuntos:
Candida albicans
oral colonization
pathogenicity
inflammation hyphal network
cAMP-PKA pathway
BRG1
Acesso em linha:https://journals.asm.org/doi/10.1128/mbio.00415-26
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