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The pathogenic role of succinate-SUCNR1: a critical function that induces renal fibrosis via M2 macrophage

Abstract Background Renal fibrosis significantly contributes to the progressive loss of kidney function in chronic kidney disease (CKD), with alternatively activated M2 macrophages playing a crucial role in this progression. The serum succinate level is consistently elevated in individuals with diab...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Min Pu, Jing Zhang, Fuyan Hong, Yan Wang, Chengwei Zhang, Yongcheng Zeng, Zhenzhen Fang, Weiwei Qi, Xia Yang, Guoquan Gao, Ti Zhou
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2024-01-01
Rangatū:Cell Communication and Signaling
Urunga tuihono:https://doi.org/10.1186/s12964-024-01481-5
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