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Computational Screening and Experimental Validation of Inhibitor Targeting the Complex Formation of Grb14 and Insulin Receptor

The development of drugs targeting gene products associated with insulin resistance holds the potential to enhance our understanding of type 2 diabetes mellitus (T2DM). The virtual screening, based on a three-dimensional (3D) protein structure, is a potential technique to accelerate the development...

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Autors principals: Yosuke Ochi, Takanori Matsui, Keitaro Inoue, Kohei Monobe, Hiroshi Sakamoto, Shunsuke Aoki, Junichi Taira
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2023-12-01
Col·lecció:Molecules
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Accés en línia:https://www.mdpi.com/1420-3049/29/1/198
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