Telomere length correlates with disease severity and inflammation in sickle cell disease

ABSTRACT Background: Telomeres, the ends of linear chromosomes, shorten during mitotic cell division and erosion may be aggravated by inflammation or proliferative and oxidative stress. As the bone marrow is under hyperproliferative pressure in sickle cell disease and several tissues are submitted...

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Autors principals:	Marina Pereira Colella, Barbara A. Santana, Nicola Conran, Vinicius Tomazini, Fernando F. Costa, Rodrigo T. Calado, Sara T. Olalla Saad
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier
Col·lecció:	Revista Brasileira de Hematologia e Hemoterapia
Matèries:	Sickle cell disease Telomere length Inflammation
Accés en línia:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842017000200140&lng=en&tlng=en
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