Neutrophil extracellular traps-triggered impaired autophagic flux via METTL3 underlies sepsis-associated acute lung injury

Abstract Neutrophil extracellular traps (NETs) assist pathogen clearance, while excessive NETs formation is associated with exacerbated inflammatory responses and tissue injury in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). Autophagy is generally considered to be a protective...

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Bibliografiske detaljer

Principais autores:	Mengdi Qu, Zhaoyuan Chen, Zhiyun Qiu, Ke Nan, Yanghanzhao Wang, Yuxin Shi, Yuwen Shao, Ziwen Zhong, Shuainan Zhu, Kefang Guo, Wankun Chen, Xihua Lu, Zhiping Wang, Hao Zhang, Changhong Miao
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2022-08-01
Serier:	Cell Death Discovery
Online adgang:	https://doi.org/10.1038/s41420-022-01166-3
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