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The Metabolic Response to Infection With Wolbachia Implicates the Insulin/Insulin-Like-Growth Factor and Hypoxia Signaling Pathways in Drosophila melanogaster

The endosymbiotic bacteria, Wolbachia, are best known for their ability to manipulate insect-host reproduction systems that enhance their vertical transmission within host populations. Increasingly, Wolbachia have been shown to depend on their hosts' metabolism for survival and in turn provision met...

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Principais autores: Denni Currin-Ross, Luke Husdell, Gregory K. Pierens, Nicholas E. Mok, Scott L. O'Neill, Horst Joachim Schirra, Jeremy C. Brownlie
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-03-01
Serier:Frontiers in Ecology and Evolution
Fag:
Wolbachia
Drosophila melanogaster
iron
metabolomics
NMR
insulin/insulin-like growth factor signaling (IIS) pathway
Online adgang:https://www.frontiersin.org/articles/10.3389/fevo.2021.623561/full
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