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Didang Tang alleviates neuronal ferroptosis after intracerebral hemorrhage by modulating the PERK/eIF2α/ATF4/CHOP/GPX4 signaling pathway

IntroductionFerroptosis is a crucial process contributing to neuronal damage following intracerebral hemorrhage (ICH). Didang Tang (DDT), a traditional therapeutic, has been used clinically to manage ICH for many years, yet the molecular mechanisms by which by DDT protects neurons from ferroptosis a...

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Principais autores: Jing Lu, Hanying Xu, Li Li, Xiaolei Tang, Ying Zhang, Dongmei Zhang, Peng Xu, Liwei Sun, Jian Wang
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2024-10-01
סדרה:Frontiers in Pharmacology
נושאים:
Didang Tang
ferroptosis
intracerebral hemorrhage
endoplasmic reticulum stress
HPLC
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fphar.2024.1472813/full
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