The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra

Abstract Background The Hydra head organizer acts as a signaling center that initiates and maintains the primary body axis in steady state polyps and during budding or regeneration. Wnt/beta-Catenin signaling functions as a primary cue controlling this process, but how Wnt ligand activity is locally...

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Autores principales:	Berenice Ziegler, Irene Yiallouros, Benjamin Trageser, Sumit Kumar, Moritz Mercker, Svenja Kling, Maike Fath, Uwe Warnken, Martina Schnölzer, Thomas W. Holstein, Markus Hartl, Anna Marciniak-Czochra, Jörg Stetefeld, Walter Stöcker, Suat Özbek
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2021-06-01
Colección:	BMC Biology
Materias:	Hydra Wnt signaling Proteinase Astacin Axis formation
Acceso en línea:	https://doi.org/10.1186/s12915-021-01046-9
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