Host-pathogen relationship in retreated tuberculosis with major rifampicin resistance–conferring mutations

IntroductionIt is assumed that host defense systems eliminating the pathogen and regulating tissue damage make a strong impact on the outcome of tuberculosis (TB) disease and that these processes are affected by rifampicin (RIF) resistance–conferring mutations of Mycobacterium tuberculosis (Mtb). Ho...

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Principais autores:	Nguyen Thi Le Hang, Minako Hijikata, Shinji Maeda, Pham Huu Thuong, Hoang Van Huan, Nguyen Phuong Hoang, Do Bang Tam, Pham Thu Anh, Nguyen Thu Huyen, Vu Cao Cuong, Nobuyuki Kobayashi, Keiko Wakabayashi, Akiko Miyabayashi, Shintaro Seto, Naoto Keicho
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-07-01
coleção:	Frontiers in Microbiology
Assuntos:	Mycobacterium tuberculosis recurrence rifampicin resistance rpoB variants whole genome sequencing blood transcriptomic signatures
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1187390/full
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