3D-QSAR and virtual screening of 5α-reductase Ⅱ inhibitors of 6-azasteroids
Three-dimensional quantitative structure-activity relationship analysis of 37 6-azasteroids inhibitors was carried out by Topomer CoMFA. The new model’s cross validation and correlation coefficient were q2=0.774 and r2=0.965, respectively. The results show that the model has good prediction ability...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Editorial Department of Journal of Sichuan University (Natural Science Edition)
2018-01-01
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| Series: | 四川大学学报. 自然科学版 |
| Assuntos: | |
| Acceso en liña: | http://science.scu.edu.cn/thesisDetails?columnId=45827567&Fpath=home&index=0 |
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