Extracellular vesicle heterogeneity through the lens of multiomics

Summary: Extracellular vesicles (EVs) are heterogeneous in size, biogenesis, content, and function. Aggressive cancer cells release a distinct, poorly characterized, and particularly large EV subtype, namely large oncosomes (LOs). This study employs an optimized method to improve LO yields and integ...

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Bibliografiske detaljer

Principais autores:	Taylon F. Silva, Elizabeth Hutchins, Wenyan Zhao, Yari Ciani, Minhyung Kim, Emily Ko, Javier Mariscal, Zhuyu Qiu, Fatima Bedier, Agnes Kittel, Bo Zhou, Yang Wang, Megan Hall, Francesca Galasso, Rebecca Reiman, Michael R. Freeman, Sarah Parker, Jennifer Van Eyk, Wei Yang, Edwin Posadas, Jlenia Guarnerio, John Nolan, Clotilde Théry, Andries Zijlstra, Shannon Stott, Sungyong You, Francesca Demichelis, Paul C. Boutros, Kendall Van Keuren-Jensen, Dolores Di Vizio
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2025-07-01
Serier:	Cell Reports Medicine
Fag:	extracellular vesicles large oncosomes multiomics proteomic transcriptomic prostate cancer
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2666379125002344
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