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Comprehensive Powder Rheological Characterization of Fifteen Lactose-Based Co-Processed and Single-Component Excipients Using FT4 Powder Rheometry and European Pharmacopoeia Methods: A Multi-Parameter Comparative and Correlative Study

<b>Background/Objectives</b>: Co-processed excipients (CPEs) are designed for direct compression through particle engineering, yet comprehensive powder rheological profiles systematically comparing advanced and traditional characterization methods remain limited. This study characterized fifteen lac...

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Principais autores: Martin Röttig, Bertram Wolf, Jessica Zwanzig, Fabian Herz, Florian Priese
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2026-04-01
Series:Pharmaceutics
Assuntos:
co-processed excipients
FT4 powder rheometer
pharmacopoeia
powder flow
lactose
direct compression
Acceso en liña:https://www.mdpi.com/1999-4923/18/5/558
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