Optimization of the Routine Approach for Label-Free Single-Cell Proteomics Using timsTOF Pro2 MS

Single-cell proteomics (SCP) aims to resolve protein heterogeneity among cells within tissue microenvironments. Single-cell proteomics analysis inherently relies on high-sensitivity mass spectrometry platforms. In this study, a series of optimizations for SCP analysis in a routine approach based on...

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Egile Nagusiak:	Li-ying CHEN, Lin-yuan FAN, Yue-fei ZHANG, Yu-ying HUANG, Jun LI, Ning XU, Yan REN, Si-qi LIU
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Editorial Board of Journal of Chinese Mass Spectrometry Society 2026-05-01
Saila:	Zhipu Xuebao
Gaiak:	label-free single-cell proteomics timstof pro2 data-independent acquisition (dia) workflow optimization
Sarrera elektronikoa:	https://zpxb.xml-journal.net/article/doi/10.7538/zpxb.2025.0164
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