Nuclear Condensates of WW Domain‐Containing Adaptor With Coiled‐Coil Regulate Mitophagy via Alternative Splicing

Abstract Biomolecular condensates segregate nuclei into discrete regions, facilitating the execution of distinct biological functions. Here, it is identified that the WW domain containing adaptor with coiled‐coil (WAC) is localized to nuclear speckles via its WW domain and plays a pivotal role in re...

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Hlavní autoři:	Jiahe Wang, Yi Fan, Guowen Luo, Liang Xiong, Lijie Wang, Zhuoxuan Wu, Jiayi Wang, Zhengying Peng, Clifford J Rosen, Kefeng Lu, Junjun Jing, Quan Yuan, Zhenwei Zhang, Chenchen Zhou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2025-03-01
Edice:	Advanced Science
Témata:	mitophagy nuclear speckles phase‐separated biomolecular condensates pre‐mRNA splicing snRNP WAC
On-line přístup:	https://doi.org/10.1002/advs.202406759
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