Untargeted metabolomics for triaging of cytochrome b inhibitors during Chagas' disease drug discovery.
Chagas' disease, caused by infection with the protozoan parasite Trypanosoma cruzi, is a potentially fatal condition for which new treatments are urgently needed. Due to the lack of validated drug targets, phenotypic screening followed by target deconvolution is the dominant approach in Chagas' dise...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2026-01-01
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| coleção: | PLoS Neglected Tropical Diseases |
| Acesso em linha: | https://doi.org/10.1371/journal.pntd.0013917 |
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