In vitro neutralization of low dose inocula at physiological concentrations of a monoclonal antibody which protects macaques against SHIV challenge.

BACKGROUND: Passive transfer of antibodies can be protective in the simian human immunodeficiency virus (SHIV)--rhesus macaque challenge model. The human monoclonal antibody IgG1 b12 neutralizes human immunodeficiency type 1 (HIV-1) in vitro and protects against challenge by SHIV. Our hypothesis is...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	David Davis, Wim Koornstra, Zahra Fagrouch, Ernst J Verschoor, Jonathan L Heeney, Willy M J M Bogers
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	http://europepmc.org/articles/PMC3745472?pdf=render
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