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Itraconazole resistance in Madurella fahalii linked to a distinct homolog of the gene encoding cytochrome P450 14-α sterol demethylase (CYP51).

<h4>Background</h4>Mycetoma is a deep fungal infection caused by several microorganisms, with Madurella mycetomatis being the most common causative agent. Another related species, Madurella fahalii, is also known to cause eumycetoma. However, unlike M. mycetomatis, M. fahalii exhibits resistance to...

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Principais autores: Isato Yoshioka, Ahmed Hassan Fahal, Satoshi Kaneko, Wei Cao, Takashi Yaguchi
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2025-03-01
Series:PLoS Neglected Tropical Diseases
Acceso en liña:https://doi.org/10.1371/journal.pntd.0012623
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