Cardiac and skeletal actin substrates uniquely tune cardiac myosin strain-dependent mechanics

Cardiac ventricular myosin (βmys) translates actin by transducing ATP free energy into mechanical work during muscle contraction. Unitary βmys translation of actin is the step-size. In vitro and in vivo βmys regulates contractile force and velocity autonomously by remixing three different step-sizes...

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Bibliografske podrobnosti

Principais autores:	Yihua Wang, Katalin Ajtai, Thomas P. Burghardt
Format:	Artigo
Jezik:	Inglês
Izdano:	The Royal Society 2018-11-01
Serija:	Open Biology
Teme:	cardiac actin ventricular myosin force–velocity strain-sensitive regulation actin binding myosin essential light chain elc n-terminus/cardiac actin contact
Online dostop:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.180143
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