Immune complexes-mediated activation of neutrophils in systemic lupus erythematosus is dependent on RNA recognition by toll-like receptor 8

IntroductionNeutrophil activation is important in systemic lupus erythematosus (SLE). We previously demonstrated that ribonucleoprotein (RNP) immune complexes (ICs) promoted neutrophil activation in a TLR7/8-dependent manner. However, it remains unclear if this mechanism occurs in patients. Here, we...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Ting Wang, Runa Kuley, Payton Hermanson, Peirou Chu, Christopher Pohlmeyer, Jayamary Divya Ravichandar, David Lopez, Gundula Min-Oo, Natasha Crellin, Ching Shang, Christian Lood
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2024-12-01
Reeks:	Frontiers in Immunology
Onderwerpen:	immune complexes neutrophils systemic lupus erythematosus toll-like receptor 8 RNA recognition
Online toegang:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1515469/full
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!