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Tieing together loose ends: telomere instability in cancer and aging

Telomere maintenance is essential for maintaining genome integrity in both normal and cancer cells. Without functional telomeres, chromosomes lose their protective structure and undergo fusion and breakage events that drive further genome instability, including cell arrest or death. One means by whi...

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Hlavní autoři: Gustavo Borges, Mélanie Criqui, Lea Harrington
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2022-09-01
Edice:Molecular Oncology
Témata:
On-line přístup:https://doi.org/10.1002/1878-0261.13299
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