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Arene Ruthenium(II) Complexes with Phosphorous Ligands as Possible Anticancer Agents

Ruthenium(II) complexes of formula [Ru(?6-arene)Cl2 (PTA)] (RAPTA) are potential anticancer drugs with notable antimetastatic and antiangiogenic activity, which are now pointing to clinical trials. Following the great interest aroused by these compounds, a variety of RAPTA derivatives, obt...

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Principais autores: Lorenzo Biancalana, Guido Pampaloni, Fabio Marchetti
Formato: Artigo
Idioma:Alemão
Publicado em: Swiss Chemical Society 2017-09-01
coleção:CHIMIA
Assuntos:
Anticancer drugs
Bioactive groups
Phosphorus ligand
Rapta
Ruthenium arene compounds
Acesso em linha:https://www.chimia.ch/chimia/article/view/1648
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