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Mechanism of METTL14-mediated RAD21 mRNA epigenetic transcriptome modification in inhibiting thyroid cancer development

Abstract Objective This study investigated the mechanism of methyltransferase-like 14 (METTL14)-mediated epigenetic transcriptome modification of RAD21 mRNA in inhibiting thyroid cancer (TC) development. Methods TCGA and Starbase databases were used to predict the differential expression of METTL14...

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Principais autores: Yinzhe Ge, Chen Qin, Mang Xiao
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:World Journal of Surgical Oncology
Fag:
Thyroid cancer
METTL14
RAD21
M6A
Proliferation
Apoptosis
Online adgang:https://doi.org/10.1186/s12957-025-04024-5
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