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5-Aminolevulinic Acid photodynamic therapy treats HPV-associated diseases by promoting M1 macrophage polarization through STEAP3/p53/SLC7A11-mediated ferroptosis

Background: Human papillomavirus (HPV) infection is a major driver of various malignancies, accounting for approximately 90% of cervical cancer cases and 70% of oropharyngeal cancer cases worldwide, yet therapies for persistent lesions remain limited. 5-aminolevulinic acid photodynamic therapy (ALA-...

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Principais autores: Rui Xu, Aijia Ding, Bichun Xu, Jing Shen, Junpeng Li, Hui Liu, Yuan Deng, Youfan Zhang, Yue Zheng, Kang Zeng
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-06-01
Serier:Photodiagnosis and Photodynamic Therapy
Fag:
ALA-PDT
Ferroptosis
Macrophage polarization
HPV
Photodynamic Therapy
Online adgang:http://www.sciencedirect.com/science/article/pii/S1572100026001900
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