Ezetimibe Promotes Brush Border Membrane-to-Lumen Cholesterol Efflux in the Small Intestine.

Ezetimibe inhibits Niemann-Pick C1-like 1 (NPC1L1), an apical membrane cholesterol transporter of enterocytes, thereby reduces intestinal cholesterol absorption. This treatment also increases extrahepatic reverse cholesterol transport via an undefined mechanism. To explore this, we employed a trans-...

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Autors principals:	Takanari Nakano, Ikuo Inoue, Yasuhiro Takenaka, Hiraku Ono, Shigehiro Katayama, Takuya Awata, Takayuki Murakoshi
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2016-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC4811413?pdf=render
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