Genome-wide MNase hypersensitivity assay unveils distinct classes of open chromatin associated with H3K27me3 and DNA methylation in Arabidopsis thaliana

Abstract Background Regulation of transcription depends on interactions between cis-regulatory elements (CREs) and regulatory proteins. Active CREs are imbedded in open chromatin that are accessible to nucleases. Several techniques, including DNase-seq, which is based on nuclease DNase I, and ATAC-s...

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Detalhes bibliográficos

Principais autores:	Hainan Zhao, Wenli Zhang, Tao Zhang, Yuan Lin, Yaodong Hu, Chao Fang, Jiming Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-02-01
coleção:	Genome Biology
Assuntos:	Open chromatin cis-regulatory elements Histone modification DNA methylation DNase-seq ATAC-seq
Acesso em linha:	https://doi.org/10.1186/s13059-020-1927-5
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