Investigating Connectivity Deficits in Alzheimer’s Disease Using a Novel 3D Bioprinted Model Designed to Quantify Neurite Outgrowth

Here, we present a novel 3D bioprinted model of the forebrain cortex designed to quantify neurite outgrowth across a hydrogel bridge. To validate this model, we cultured Alzheimer’s disease (AD) forebrain cortical populations derived from human iPSCs carrying APP (amyloid precursor protein) mutation...

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Autori principali:	Chloe Whitehouse, Ellie Bravington, Anirudh Patir, Wei Wei, Janet Brownlees, Yufang He, Nicola Corbett
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-02-01
Serie:	Bioengineering
Soggetti:	3D bioprinting Alzheimer’s disease iPSC culture neurite outgrowth
Accesso online:	https://www.mdpi.com/2306-5354/12/3/245
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