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Investigation of the methylerythritol 4-phosphate pathway for microbial terpenoid production through metabolic control analysis

Abstract Background Terpenoids are of high interest as chemical building blocks and pharmaceuticals. In microbes, terpenoids can be synthesized via the methylerythritol phosphate (MEP) or mevalonate (MVA) pathways. Although the MEP pathway has a higher theoretical yield, metabolic engineering has me...

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Principais autores: Daniel Christoph Volke, Johann Rohwer, Rainer Fischer, Stefan Jennewein
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-11-01
coleção:Microbial Cell Factories
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Acesso em linha:http://link.springer.com/article/10.1186/s12934-019-1235-5
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