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Role of Ezrin/Radixin/Moesin in the Surface Localization of Programmed Cell Death Ligand-1 in Human Colon Adenocarcinoma LS180 Cells

Programmed cell death ligand-1 (PD-L1), an immune checkpoint protein highly expressed on the cell surface in various cancer cell types, binds to programmed cell death-1 (PD-1), leading to T-cell dysfunction and tumor survival. Despite clinical successes of PD-1/PD-L1 blockade therapies, patients wit...

詳細記述

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書誌詳細
主要な著者: Takuro Kobori, Chihiro Tanaka, Mayuka Tameishi, Yoko Urashima, Takuya Ito, Tokio Obata
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2021-08-01
シリーズ:Pharmaceuticals
主題:
オンライン・アクセス:https://www.mdpi.com/1424-8247/14/9/864
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