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γ-terpinene inhibits the progression of hepatocellular carcinoma by regulating the PTEN/PI3K/Akt signaling pathway mediated glycolysis

Abstract Hepatocellular carcinoma (HCC) is a lethal malignancy. This study was designed to investigate the anti-HCC effects of the natural monoterpene compound γ-terpinene (γ-TPN) and its potential mechanism regulating the PTEN/PI3K/Akt pathway and glycolysis. The effects of γ-TPN on cell proliferat...

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Principais autores: Dingding Zhang, Zhaoxin Gong, Hualong Li, Nan Cai
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2026-04-01
Serier:Scientific Reports
Fag:
γ-terpinene
Hepatocellular carcinoma
PTEN/PI3K/Akt signaling pathway
Online adgang:https://doi.org/10.1038/s41598-026-47676-3
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