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Plasma NfL and cognitive functioning in older adults: The moderating role of HDL cholesterol

Abstract BACKGROUND AND OBJECTIVES Plasma neurofilament light chain (NfL) is a marker of neuroaxonal injury associated with cognitive decline. High‐density lipoprotein (HDL) cholesterol has neuroprotective properties, but its interaction with neurodegeneration remains unclear. This study examined wh...

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Principais autores: Ramkrishna K. Singh, Semere Bekena, Yiqi Zhu, Carlos Cruchaga, Steven E. Arnold, Beau M. Ances, Ganesh M. Babulal
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-10-01
Serier:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Fag:
aging
biomarkers
cognitive performance
cross‐sectional study
high‐density lipoprotein
interaction effects
Online adgang:https://doi.org/10.1002/dad2.70205
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