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Regulation of localization and function of the transcriptional co-activator YAP by angiomotin

The Hippo-YAP pathway is a central regulator of cell contact inhibition, proliferation and death. There are conflicting reports regarding the role of Angiomotin (Amot) in regulating this pathway. While some studies suggest a YAP-inhibitory function other studies indicate Amot is required for YAP act...

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Principais autores: Susana Moleirinho, Sany Hoxha, Vinay Mandati, Graziella Curtale, Scott Troutman, Ursula Ehmer, Joseph L Kissil
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications Ltd 2017-05-01
Serija:eLife
Teme:
Online dostop:https://elifesciences.org/articles/23966
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