Understanding MHC class I presentation of viral antigens by human dendritic cells as a basis for rational design of therapeutic vaccines

Effective viral clearance requires the induction of virus-specific CD8+ cytotoxic T lymphocytes (CTL). Since dendritic cells (DC) have a central role in initiating and shaping virus-specific CTL responses, it is important to understand how DC initiate virus-specific CTL responses. Some viruses can d...

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Principais autores:	Nadine eVan Montfoort, Evelyn evan der Aa, Andrea Monique Woltman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2014-04-01
coleção:	Frontiers in Immunology
Assuntos:	Immunotherapy virus virus-host interaction cross-presentation viral immunity human dendritic cell
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00182/full
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