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Immunoglobulin G1 Allotype Influences Antibody Subclass Distribution in Response to HIV gp140 Vaccination

Antibody subclasses exhibit extensive polymorphisms (allotypes) that could potentially impact the quality of HIV-vaccine induced B cell responses. Allotypes of immunoglobulin (Ig) G1, the most abundant serum antibody, have been shown to display altered functional properties in regard to serum half-l...

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Autori principali: Sven Kratochvil, Paul F. McKay, Amy W. Chung, Stephen J. Kent, Jill Gilmour, Robin J. Shattock
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017-12-01
Serie:Frontiers in Immunology
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Accesso online:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01883/full
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