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Agmatine-attenuated cognitive and social deficits in subchronic MK-801 model of schizophrenia in rats

INTRODUCTION: Schizophrenia is one of the most severe psychiatric disorders with about 1% prevalence. It has been proved that glutamatergic N-methyl-d-aspartate (NMDA) receptor antagonists such as MK-801 and phencyclidine cause schizophrenia-like behaviours in rodents. Agmatine is an endogenous amin...

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Autori principali: Gokhan Unal, Alpay Ates, Feyza Aricioglu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mesut Çetin 2018-07-01
Serie:Psychiatry and Clinical Psychopharmacology
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Accesso online:http://dx.doi.org/10.1080/24750573.2018.1426696
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