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Hydroxyurea promotes brain development in children with sickle cell anemia

Sickle cell anemia (SCA) is associated with chronic anemia and cerebrovascular dysfunction, leading to progressive brain atrophy. Hydroxyurea (HU), a disease-modifying therapy, improves hematologic parameters and reduces stroke risk, but its long-term effects on brain development remain unclear. Eve...

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Kaydedildi:
Asıl Yazarlar: Yonca Cam, Jingyi Zhang, Igor Dedkov, Amy Ouyang, Josiah B. Lewis, Michael M. Binkley, Amy E. Mirro, Slim Fellah, Heather Roberts, Joshua S. Shimony, Hongyu An, Jin-Moo Lee, Andria L. Ford, Melanie E. Fields, Kristin P. Guilliams
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2026-09-01
Seri Bilgileri:Brain Research Bulletin
Konular:
Sickle cell disease
Hydroxyurea
Neurodevelopment
Pediatric neurology
Brain imaging
Online Erişim:http://www.sciencedirect.com/science/article/pii/S0361923026003217
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